Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09HET
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| Former ID |
DIB020195
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| Drug Name |
L-beta-BA
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| Synonyms |
L-beta-threo-benzyl-aspartate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C11H13NO4
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| Canonical SMILES |
C1=CC=C(C=C1)CC(C(C(=O)O)N)C(=O)O
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| InChI |
1S/C11H13NO4/c12-9(11(15)16)8(10(13)14)6-7-4-2-1-3-5-7/h1-5,8-9H,6,12H2,(H,13,14)(H,15,16)/t8-,9-/m0/s1
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| InChIKey |
KMVYGTIPJNGNRD-IUCAKERBSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Excitatory amino acid transporter 3 (SLC1A1) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4625). | |||
| REF 2 | The substituted aspartate analogue L-beta-threo-benzyl-aspartate preferentially inhibits the neuronal excitatory amino acid transporter EAAT3. Neuropharmacology. 2005 Nov;49(6):850-61. | |||
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