Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09CUR
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| Former ID |
DNCL002496
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| Drug Name |
Trans-sodium crocetinate
|
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| Drug Type |
Small molecular drug
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| Indication | Glioblastoma of brain [ICD-11: 2A00.00; ICD-10: C71] | Phase 3 | [1] | |
| Brain metastases [ICD-11: 2D50; ICD-10: C79.3; ICD-9: 198.3] | Phase 1 | [2], [3] | ||
| Company |
Diffusion Pharmaceuticals
|
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| Structure |
 |
Download2D MOL
|
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| Formula |
C20H22Na2O4
|
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| Canonical SMILES |
CC(=CC=CC=C(C)C=CC=C(C)C(=O)[O-])C=CC=C(C)C(=O)[O-].[Na+].[Na+]
|
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| InChI |
1S/C20H24O4.2Na/c1-15(11-7-13-17(3)19(21)22)9-5-6-10-16(2)12-8-14-18(4)20(23)24;;/h5-14H,1-4H3,(H,21,22)(H,23,24);;/q;2*+1/p-2/b6-5+,11-7+,12-8+,15-9+,16-10+,17-13+,18-14+;;
|
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| InChIKey |
RMDMBHQVNHQDDD-VFWKRBOSSA-L
|
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| CAS Number |
CAS 591230-99-8
|
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT03393000) Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjects (INTACT). U.S. National Institutes of Health. | |||
| REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 3 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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