Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09CNM
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| Drug Name |
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-(2-fluoro-phenyl)-2H-pyrazol-3-ylamine
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| Synonyms |
SCHEMBL686446; CHEMBL3639845; BDBM123985; US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-(2-fluoro-phenyl)-2H-pyrazol-3-ylamine
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C17H12F2N4OS
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| Canonical SMILES |
COC1=C(C=C2C(=C1)SC(=N2)C3=C(NN=C3N)C4=CC=CC=C4F)F
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| InChI |
1S/C17H12F2N4OS/c1-24-12-7-13-11(6-10(12)19)21-17(25-13)14-15(22-23-16(14)20)8-4-2-3-5-9(8)18/h2-7H,1H3,(H3,20,22,23)
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| InChIKey |
YMZGLBIKIDCVFV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Integrin-linked protein kinase 1 (ILK) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Integrin-linked protein kinase 1 (ILK) | Target's Patent Info | [1] | |
| NetPath Pathway | TCR Signaling Pathway | |||
| FSH Signaling Pathway | ||||
| Panther Pathway | Integrin signalling pathway | |||
| Pathway Interaction Database | Osteopontin-mediated events | |||
| Integrin-linked kinase signaling | ||||
| Integrins in angiogenesis | ||||
| Reactome | Localization of the PINCH-ILK-PARVIN complex to focal adhesions | |||
| WikiPathways | Eukaryotic Transcription Initiation | |||
| Focal Adhesion | ||||
| Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| Integrin-mediated Cell Adhesion | ||||
| Cell junction organization | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pyrazolylbenzothiazole derivatives and their use as therapeutic agents. US8754233. | |||
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