Drug Information
Drug General Information | Top | |||
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Drug ID |
D09CEY
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Former ID |
DIB003129
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Drug Name |
SKL-PSY
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Synonyms |
5-HT 1a receptor modulator (psychiatric disorder), SK Life Science; 5-HT 1a receptor modulator (schizophrenia/depression), SK Life science
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Indication | Bipolar disorder [ICD-11: 6A60; ICD-10: F31] | Phase 1 | [1] | |
Company |
SK Life Science
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Target and Pathway | Top | |||
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Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Modulator | [2] |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
5HT1 type receptor mediated signaling pathway | ||||
Reactome | Serotonin receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Serotonin HTR1 Group and FOS Pathway | |||
SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Clinical pipeline report, company report or official report of SK Biopharmaceuticals. | |||
REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1). |
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