Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09AFM
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| Former ID |
DIB018836
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| Drug Name |
AMI-1
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| Synonyms |
AMI1; AMI 1
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C21H14N2Na2O9S2
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| Canonical SMILES |
C1=CC2=C(C=C(C=C2C=C1NC(=O)NC3=CC4=CC(=CC(=C4C=C3)O)S(=O)(=O)[O-])S(=O)(=O)[O-])O.[Na+].[Na+]
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| InChI |
1S/C21H16N2O9S2.2Na/c24-19-9-15(33(27,28)29)7-11-5-13(1-3-17(11)19)22-21(26)23-14-2-4-18-12(6-14)8-16(10-20(18)25)34(30,31)32;;/h1-10,24-25H,(H2,22,23,26)(H,27,28,29)(H,30,31,32);;/q;2*+1/p-2
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| InChIKey |
MOUNHKKCIGVIDI-UHFFFAOYSA-L
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| CAS Number |
CAS 20324-87-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
68470, 99055, 637782, 4491422, 8191104, 11136630, 14884509, 43123906, 47960044, 48334810, 76349672, 93618358, 93620666, 103121135, 103509337, 104084507, 104338804, 117633372, 118846456, 125340254, 126688031, 128895200, 135150718, 135594720, 135684181, 136375581, 151993072, 160817581, 162036259, 162180549, 163303711, 163883360, 174477366, 176326246, 178103607, 184539128, 186021354, 223536520, 223658070, 228767902, 249849635, 250180364, 250228324, 252039027, 252303647, 252343171
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Protein arginine methyltransferase 1 (PRMT1) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7028). | |||
| REF 2 | Small molecule regulators of protein arginine methyltransferases. J Biol Chem. 2004 Jun 4;279(23):23892-9. | |||
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