Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08ZRW
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| Former ID |
DNC001557
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| Drug Name |
Cantide + Cisplatin
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| Synonyms |
cis-Diaminedichloroplatinum; CPDC; cis-Diamminedichlorplatine; cis-Dichlorodiamine platinum; Diamminedichloroplatinum; Platinum diamine dichloride; Platinum, diamminedichloro-; trans-Diaminedichloroplatinum; NCGC00090759-01; DSSTox_CID_4983; DSSTox_RID_77611; DSSTox_GSID_24983; CAS-15663-27-1; Platiblastin; cisplatin complex; DDPt; cis-Platinum(II); Pt(II) Complex; cis Pt II; CPDD; dichloroplatinumdiamine; Platinum(IV) Complex; Platinum (II) complex; Neuro_000055; cis-Platinum diamminedichloride; DTXSID4024983; MolPort-003-983-464
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| Drug Type |
Combination drug (Antisense drug)
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| Indication | Tumour [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Investigative | [1] | |
| Therapeutic Class |
Antisense
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| Structure |
 |
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| Formula |
Cl2H4N2Pt
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| Canonical SMILES |
[NH2-].[NH2-].Cl[Pt+2]Cl
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| InChI |
1S/2ClH.2H2N.Pt/h2*1H;2*1H2;/q;;2*-1;+4/p-2
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| InChIKey |
DQLATGHUWYMOKM-UHFFFAOYSA-L
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| CAS Number |
CAS 26035-31-4
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| PubChem Compound ID | ||||
| ADReCS Drug ID | BADD_D00643 | |||
| SuperDrug ATC ID |
L01XA01
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| SuperDrug CAS ID |
cas=015663271
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | . | [1] |
| KEGG Pathway | HTLV-I infection | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
| Regulation of Telomerase | ||||
| IL2 signaling events mediated by PI3K | ||||
| Regulation of nuclear beta catenin signaling and target gene transcription | ||||
| HIF-1-alpha transcription factor network | ||||
| Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
| WikiPathways | TGF beta Signaling Pathway | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Telomere Maintenance | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design and development of antisense drugs. Expert Opin. Drug Discov. 2008 3(10):1189-1207. | |||
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