Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08XGI
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| Former ID |
DNC004123
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| Drug Name |
(1-Phenethyl-piperidin-4-yl)-phenyl-methanone
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| Synonyms |
CHEMBL19589; (1-Phenethyl-piperidin-4-yl)-phenyl-methanone; SCHEMBL7839803; GEFOLRNTTIQKBZ-UHFFFAOYSA-N; ZINC13740924; BDBM50034203; Phenyl(1-phenethyl-4-piperidinyl) ketone; phenyl-[1-(2-phenylethyl)-4-piperidyl]-ketone
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H23NO
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| Canonical SMILES |
C1CN(CCC1C(=O)C2=CC=CC=C2)CCC3=CC=CC=C3
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| InChI |
1S/C20H23NO/c22-20(18-9-5-2-6-10-18)19-12-15-21(16-13-19)14-11-17-7-3-1-4-8-17/h1-10,19H,11-16H2
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| InChIKey |
GEFOLRNTTIQKBZ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Current and novel approaches to the drug treatment of schizophrenia. J Med Chem. 2001 Feb 15;44(4):477-501. | |||
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