Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08VTS
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| Former ID |
DIB020353
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| Drug Name |
MI-1148
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| Synonyms |
4-guanidinomethyl-phenylacteyl-Arg-Tle-Arg-4-amidinobenzylamide; para-guanidinomethyl-Phac-R-Tle-R-Amba
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C36H57N15O4
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| Canonical SMILES |
CC(C)(C)C(C(=O)NC(CCCN=C(N)N)C(=O)NCC1=CC=C(C=C1)C(=N)N)NC(=O)C(CCCN=C(N)N)NC(=O)CC2=CC=C(C=C2)CN=C(N)N
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| InChI |
1S/C36H57N15O4/c1-36(2,3)28(32(55)50-25(6-4-16-45-33(39)40)30(53)47-19-23-12-14-24(15-13-23)29(37)38)51-31(54)26(7-5-17-46-34(41)42)49-27(52)18-21-8-10-22(11-9-21)20-48-35(43)44/h8-15,25-26,28H,4-7,16-20H2,1-3H3,(H3,37,38)(H,47,53)(H,49,52)(H,50,55)(H,51,54)(H4,39,40,45)(H4,41,42,46)(H4,43,44,48)/t25-,26-,28+/m0/s1
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| InChIKey |
HXVPWVPTVOOCMV-UNCTUWKVSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dibasic-processing enzyme (Furin) | Target Info | Inhibitor | [1] |
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | Alzheimer disease-amyloid secretase pathway | |||
| Alzheimer disease-presenilin pathway | ||||
| Endothelin signaling pathway | ||||
| Pathway Interaction Database | Notch signaling pathway | |||
| p75(NTR)-mediated signaling | ||||
| HIF-1-alpha transcription factor network | ||||
| Glypican 3 network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel Furin Inhibitors with Potent Anti-infectious Activity. ChemMedChem. 2015 Jul;10(7):1218-31. | |||
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