Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08SLU
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| Drug Name |
US9453017, 1
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| Synonyms |
CHEMBL3925090; BDBM247409; US9453017, 1
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H27FN4O2
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| Canonical SMILES |
C1CN(CCC12CNC(=O)N2C3=CC(=CC=C3)F)CCNC(=O)C4=CC5=CC=CC=C5C=C4
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| InChI |
1S/C26H27FN4O2/c27-22-6-3-7-23(17-22)31-25(33)29-18-26(31)10-13-30(14-11-26)15-12-28-24(32)21-9-8-19-4-1-2-5-20(19)16-21/h1-9,16-17H,10-15,18H2,(H,28,32)(H,29,33)
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| InChIKey |
BYFCBILNFVVIKQ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phospholipase D1 (PLD1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Phospholipase D1 (PLD1) | Target's Patent Info | [1] | |
| BioCyc | Phospholipases | |||
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Ether lipid metabolism | ||||
| Metabolic pathways | ||||
| Ras signaling pathway | ||||
| cAMP signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| Endocytosis | ||||
| Fc gamma R-mediated phagocytosis | ||||
| Glutamatergic synapse | ||||
| GnRH signaling pathway | ||||
| Pathways in cancer | ||||
| Pancreatic cancer | ||||
| Choline metabolism in cancer | ||||
| Panther Pathway | Angiogenesis | |||
| Ras Pathway | ||||
| Pathway Interaction Database | RhoA signaling pathway | |||
| Arf6 trafficking events | ||||
| CDC42 signaling events | ||||
| Arf6 downstream pathway | ||||
| mTOR signaling pathway | ||||
| ErbB1 downstream signaling | ||||
| IL8- and CXCR1-mediated signaling events | ||||
| Alpha-synuclein signaling | ||||
| Reactome | Role of phospholipids in phagocytosis | |||
| WikiPathways | EGF/EGFR Signaling Pathway | |||
| TSH signaling pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antiviral therapies with phospholipase D inhibitors. US9453017. | |||
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