Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08QHX
|
|||
| Former ID |
DCL001223
|
|||
| Drug Name |
PRX00933
|
|||
| Indication | Diabetic complication [ICD-11: 5A2Y] | Phase 2 | [1] | |
| Obesity [ICD-11: 5B81; ICD-10: E66] | Phase 2 | [1] | ||
| Company |
Proximagen Group plc
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2C receptor (HTR2C) | Target Info | Agonist | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2011 Pipeline of Proximagen Group plc. | |||
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