Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08NXX
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| Former ID |
DNC004193
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| Drug Name |
BMY-20844
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| Synonyms |
Bmy-20844; 124886-01-7; UNII-ALR3F45M10; CHEMBL88583; ALR3F45M10; 1,3-Dihydro-7,8-dimethyl-2H-imidazo(4,5-b)quinolin-2-one; 1,3-dihydro-7,8-dimethyl-2H-imidazo[4,5-b]quinolin-2-one; 2H-Imidazo[4,5-b]quinolin-2-one,1,3-dihydro-7,8-dimethyl-; 2H-Imidazo[4,5-b]quinolin-2-one, 1,3-dihydro-7,8-dimethyl-; 2H-Imidazo(4,5-b)quinolin-2-one, 1,3-dihydro-7,8-dimethyl-; AC1NUPC3; ACMC-1C2JD; SCHEMBL2457579; 7,8-dimethyl-1,3-dihydroimidazo[4,5-b]quinolin-2-one; CTK4B4100; DTXSID40154516; ODCKPUDNMNCWMR-UHFFFAOYSA-N; BDBM50000925
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C12H11N3O
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| Canonical SMILES |
CC1=C(C2=CC3=C(NC(=O)N3)N=C2C=C1)C
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| InChI |
1S/C12H11N3O/c1-6-3-4-9-8(7(6)2)5-10-11(13-9)15-12(16)14-10/h3-5H,1-2H3,(H2,13,14,15,16)
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| InChIKey |
ODCKPUDNMNCWMR-UHFFFAOYSA-N
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| CAS Number |
CAS 124886-01-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3A (PDE3A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| WikiPathways | miR-targeted genes in muscle cell - TarBase | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibitors of blood platelet cAMP phosphodiesterase. 3. 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives with enhanced aqueous solubility. J Med Chem. 1992 Jul 10;35(14):2688-96. | |||
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