Drug Information
Drug General Information | Top | |||
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Drug ID |
D08NMS
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Former ID |
DIB019379
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Drug Name |
PMID20684603C24dd
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Synonyms |
GTPL8550; BDBM50324512
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C22H20Cl2N6O
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Canonical SMILES |
CC1=NC2=NC(=CN2C(=C1CN)C3=C(C=C(C=C3)Cl)Cl)C(=O)NCCC4=CC=CC=N4
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InChI |
1S/C22H20Cl2N6O/c1-13-17(11-25)20(16-6-5-14(23)10-18(16)24)30-12-19(29-22(30)28-13)21(31)27-9-7-15-4-2-3-8-26-15/h2-6,8,10,12H,7,9,11,25H2,1H3,(H,27,31)
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InChIKey |
JGJABGSOYWQCSC-UHFFFAOYSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Dipeptidyl peptidase 4 (DPP-4) | Target Info | Inhibitor | [1] |
Dipeptidyl peptidase 8 (DPP-8) | Target Info | Inhibitor | [1] | |
Dipeptidyl peptidase 9 (DPP-9) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Protein digestion and absorption | |||
NetPath Pathway | IL2 Signaling Pathway | |||
TGF_beta_Receptor Signaling Pathway |
References | Top | |||
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REF 1 | Discovery of 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamides as potent, selective dipeptidyl peptidase-4 (DPP4) inhibitors. J Med Chem. 2010 Aug 12;53(15):5620-8. |
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