Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08NFH
|
|||
| Former ID |
DNC002502
|
|||
| Drug Name |
Alpha-Phosphoribosylpyrophosphoric Acid
|
|||
| Synonyms |
PRPP; PHOSPHORIBOSYL PYROPHOSPHATE; 5-Phospho-alpha-D-ribose 1-diphosphate; 5-Phosphoribosyl diphosphate; PRib-PP; 7540-64-9; phosphoribosylpyrophosphate; 5-Phosphoribosyl 1-pyrophosphate; Ribofuranose, 5-phosphate 1-pyrophosphate; PQGCEDQWHSBAJP-TXICZTDVSA-N; 5-Phosphorylribose 1-pyrophosphate; alpha-D-Ribofuranose 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate); 13270-65-0; 5-PHOSPHORYLRIBOSE-1-PYROPHOSPHATE; 5-phosphoribosyl-1-pyrophosphate
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C5H13O14P3
|
|||
| Canonical SMILES |
C(C1C(C(C(O1)OP(=O)(O)OP(=O)(O)O)O)O)OP(=O)(O)O
|
|||
| InChI |
1S/C5H13O14P3/c6-3-2(1-16-20(8,9)10)17-5(4(3)7)18-22(14,15)19-21(11,12)13/h2-7H,1H2,(H,14,15)(H2,8,9,10)(H2,11,12,13)/t2-,3-,4-,5-/m1/s1
|
|||
| InChIKey |
PQGCEDQWHSBAJP-TXICZTDVSA-N
|
|||
| CAS Number |
CAS 7540-64-9
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
3419, 820069, 822279, 822283, 822299, 822303, 825336, 825688, 832895, 836929, 7890051, 8025362, 8145620, 8154918, 10317395, 26709671, 29226205, 46490902, 46504019, 46504236, 46506467, 49661694, 49661696, 49693204, 52762694, 56374456, 57324128, 85149283, 85149288, 85176952, 85177095, 85786881, 92297925, 104314662, 125310657, 126523133, 127308381, 127308382, 127308383, 128952664, 134970635, 134988525, 137003190, 139137656, 140310573, 143472383, 143472386, 144187278, 144187282, 144187310
|
|||
| ChEBI ID |
CHEBI:17111
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Orotidine 5'-monophosphate decarboxylase (UMPS) | Target Info | Inhibitor | [1] |
| Plasmodium Hypoxanthine-guanine phosphoribosyltransferase (Malaria LACZ) | Target Info | Inhibitor | [1] | |
| BioCyc | Superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis | |||
| Superpathway of pyrimidine ribonucleotides de novo biosynthesis | ||||
| UMP biosynthesis | ||||
| KEGG Pathway | Pyrimidine metabolism | |||
| Drug metabolism - other enzymes | ||||
| Metabolic pathways | ||||
| Purine metabolism | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Pathwhiz Pathway | Purine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| Purine salvage | ||||
| WikiPathways | Metabolism of nucleotides | |||
| Fluoropyrimidine Activity | ||||
| Nucleotide Metabolism | ||||
| Mesodermal Commitment Pathway | ||||
| Endoderm Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.