Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08MPA
|
|||
| Former ID |
DIB009393
|
|||
| Drug Name |
AMA-76
|
|||
| Indication | Glaucoma/ocular hypertension [ICD-11: 9C61; ICD-9: 365] | Phase 2 | [1] | |
| Company |
Amakem
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Rho-associated protein kinase (ROCK) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT02136940) Multiple Dose-parallel-group Study of AMA0076 in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension. U.S. National Institutes of Health. | |||
| REF 2 | AMA0076, a novel, locally acting Rho kinase inhibitor, potently lowers intraocular pressure in New Zealand white rabbits with minimal hyperemia. Invest Ophthalmol Vis Sci. 2014 Feb 18;55(2):1006-16. | |||
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