Drug Information
Drug General Information | Top | |||
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Drug ID |
D08MEN
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Former ID |
DNC009419
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Drug Name |
KF-A5
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Synonyms |
KF-A5; CHEMBL491754; SCHEMBL10704523; BDBM50249782
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C22H28N2O
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Canonical SMILES |
CCN(CC)CCCCCN1C2=CC=CC=C2C(=O)C3=CC=CC=C31
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InChI |
1S/C22H28N2O/c1-3-23(4-2)16-10-5-11-17-24-20-14-8-6-12-18(20)22(25)19-13-7-9-15-21(19)24/h6-9,12-15H,3-5,10-11,16-17H2,1-2H3
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InChIKey |
YCWGZWYJTIJTHX-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Norepinephrine transporter (NET) | Target Info | Inhibitor | [1] |
Serotonin transporter (SERT) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Serotonergic synapse | |||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | 5HT1 type receptor mediated signaling pathway | |||
5HT2 type receptor mediated signaling pathway | ||||
5HT3 type receptor mediated signaling pathway | ||||
5HT4 type receptor mediated signaling pathway | ||||
Adrenaline and noradrenaline biosynthesis | ||||
Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
WikiPathways | Monoamine Transport | |||
SIDS Susceptibility Pathways | ||||
NRF2 pathway | ||||
Synaptic Vesicle Pathway | ||||
Serotonin Transporter Activity | ||||
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds |
References | Top | |||
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REF 1 | Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparum. Antimicrob Agents Chemother. 2007 Nov;51(11):4133-40. |
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