Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08LYB
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| Former ID |
DNC001288
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| Drug Name |
SB 239063
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| Synonyms |
SB 239063; 193551-21-2; SB239063; SB-239063; UNII-HII3DC8CPI; HII3DC8CPI; CHEMBL97162; trans-1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypyridimidin-4-yl)imidazole; CHEBI:90681; TRANS-1-(4-HYDROXYCYCLOHEXYL)-4-(4-FLUOROPHENYL)-5-(2-METHOXYPYRIMIDIN-4-YL) IMIDAZOLE; trans-4-[4-(4-Fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl]cyclohexanol; 4-[4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)imidazol-1-yl]cyclohexan-1-ol
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| Drug Type |
Small molecular drug
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| Indication | Pain [ICD-11: MG30-MG3Z] | Investigative | [1] | |
| Therapeutic Class |
Analgesics
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H21FN4O2
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| Canonical SMILES |
COC1=NC=CC(=N1)C2=C(N=CN2C3CCC(CC3)O)C4=CC=C(C=C4)F
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| InChI |
1S/C20H21FN4O2/c1-27-20-22-11-10-17(24-20)19-18(13-2-4-14(21)5-3-13)23-12-25(19)15-6-8-16(26)9-7-15/h2-5,10-12,15-16,26H,6-9H2,1H3
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| InChIKey |
ZQUSFAUAYSEREK-UHFFFAOYSA-N
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| CAS Number |
CAS 193551-21-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7646389, 7980718, 8153176, 11114250, 14803860, 14803861, 14946359, 26759488, 29224227, 49684196, 49958232, 53800549, 57322637, 75775095, 85789056, 99302843, 99437697, 103311316, 103572110, 103905255, 104001440, 104308457, 121364785, 126408087, 129941884, 129941885, 129941886, 134340494, 135686084, 135686085, 135686102, 135686103, 135698451, 137362903, 141618510, 142424129, 152258312, 160647152, 162011806, 162023368, 162248320, 162987079, 163426245, 163687366, 164764955, 174007082, 174528162, 177749070, 179148810, 179694569
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| ChEBI ID |
CHEBI:90681
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | SB-239063, a potent and selective inhibitor of p38 map kinase: preclinical pharmacokinetics and species-specific reversible isomerization. Pharm Res. 2001 Sep;18(9):1336-44. | |||
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