Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08KLL
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| Former ID |
DNC006795
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| Drug Name |
2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic acid
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| Synonyms |
CHEMBL212860; 2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic acid; SCHEMBL5664165; JDODANGOYUAOQT-UHFFFAOYSA-N; BDBM50192463; 2,3-bis[(2-chlorophenyl)methoxy]benzeneacetic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H18Cl2O4
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| Canonical SMILES |
C1=CC=C(C(=C1)COC2=CC=CC(=C2OCC3=CC=CC=C3Cl)CC(=O)O)Cl
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| InChI |
1S/C22H18Cl2O4/c23-18-9-3-1-6-16(18)13-27-20-11-5-8-15(12-21(25)26)22(20)28-14-17-7-2-4-10-19(17)24/h1-11H,12-14H2,(H,25,26)
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| InChIKey |
JDODANGOYUAOQT-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fatty acid-binding protein 4 (FABP4) | Target Info | Inhibitor | [1] |
| Fatty acid-binding protein 5 (FABP5) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | PPAR signaling pathway | |||
| NetPath Pathway | IL1 Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| Pathway Interaction Database | AP-1 transcription factor network | |||
| Reactome | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |||
| Transcriptional regulation of white adipocyte differentiation | ||||
| WikiPathways | Lipid digestion, mobilization, and transport | |||
| Transcriptional Regulation of White Adipocyte Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein. J Med Chem. 2006 Aug 10;49(16):5013-7. | |||
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