Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08IMD
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| Former ID |
DIB000002
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| Drug Name |
AZD-6495
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| Synonyms |
CHEMBL481806; SCHEMBL1276777; GTPL7711; AOB4022; AZD6495; AZD 6495; ZINC40934036; BDBM50255811; 953798-95-3; 4-[(2,4-difluorophenyl)amino]-7-ethoxy-6-(4-methylpiperazin-1-yl)quinoline-3-carboxamide
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Preclinical | [1], [2] | |
| Company |
AstraZeneca plc
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| Structure |
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Download2D MOL
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| Formula |
C23H25F2N5O2
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| Canonical SMILES |
CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=C(C=C(C=C3)F)F)C(=O)N)N4CCN(CC4)C
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| InChI |
1S/C23H25F2N5O2/c1-3-32-21-12-19-15(11-20(21)30-8-6-29(2)7-9-30)22(16(13-27-19)23(26)31)28-18-5-4-14(24)10-17(18)25/h4-5,10-13H,3,6-9H2,1-2H3,(H2,26,31)(H,27,28)
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| InChIKey |
IBHNEKVLDKCEQY-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7711). | |||
| REF 2 | Clinical pipeline report, company report or official report of AstraZeneca plc. | |||
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