Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08EEO
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| Former ID |
DIB001704
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| Drug Name |
Demobesin
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| Synonyms |
Bombesin antagonist (prostate/breast/NSCL), Biomedica lifesciences; 99mTc-Demobesin-6
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| Indication | Breast cancer [ICD-11: 2C60-2C65] | Phase 1 | [1] | |
| Company |
Biomedica Life Sciences SA
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bombesin receptor (BS) | Target Info | Antagonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Peptide GPCRs | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00989105) Technetium Tc 99m Demobesin-4 for Imaging Procedures in Patients With Prostate Cancer. U.S. National Institutes of Health. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 38). | |||
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