Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08DOE
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| Former ID |
DIB014004
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| Drug Name |
ML-04
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| Synonyms |
BTL-cg; HP-4; ML-04A; Urological therapeutics, Milkhaus; Human chorionic gonadotropin (benign prostate hyperplasia/prostatitis/cancer), Beech Tree Labs
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| Indication | Myelodysplastic syndrome [ICD-11: 2A37; ICD-9: 238.7] | Phase 2 | [1] | |
| Company |
Milkhaus Laboratory Inc
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Luteinizing hormone receptor (LHCGR) | Target Info | Modulator | [2] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Ovarian steroidogenesis | ||||
| Prolactin signaling pathway | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| Pathwhiz Pathway | Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin | |||
| Pathway Interaction Database | Arf6 signaling events | |||
| Reactome | Hormone ligand-binding receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Ovarian Infertility Genes | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00044226) A 20-Week Study of a New Treatment for Men With Benign Prostatic Hyperplasia (BPH).. U.S. National Institutes of Health. | |||
| REF 2 | Evaluation of radiolabeled ML04, a putative irreversible inhibitor of epidermal growth factor receptor, as a bioprobe for PET imaging of EGFR-overexpressing tumors. Nucl Med Biol. 2007 Jan;34(1):55-70. | |||
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