Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08BUB
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| Former ID |
DNC013332
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| Drug Name |
N2-{4-[(4-nitrobenzyl)oxy]benzyl}glycinamide
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| Synonyms |
CHEMBL242409; N2-{4-[(4-nitrobenzyl)oxy]benzyl}glycinamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H17N3O4
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| Canonical SMILES |
C1=CC(=CC=C1CNCC(=O)N)OCC2=CC=C(C=C2)[N+](=O)[O-]
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| InChI |
1S/C16H17N3O4/c17-16(20)10-18-9-12-3-7-15(8-4-12)23-11-13-1-5-14(6-2-13)19(21)22/h1-8,18H,9-11H2,(H2,17,20)
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| InChIKey |
RHNXUKDDIOAEGX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Monoamine oxidase type B (MAO-B) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of tryptophan utilization | |||
| Tryptophan degradation via tryptamine | ||||
| Dopamine degradation | ||||
| Putrescine degradation III | ||||
| Noradrenaline and adrenaline degradation | ||||
| KEGG Pathway | Glycine, serine and threonine metabolism | |||
| Arginine and proline metabolism | ||||
| Histidine metabolism | ||||
| Tyrosine metabolism | ||||
| Phenylalanine metabolism | ||||
| Tryptophan metabolism | ||||
| Drug metabolism - cytochrome P450 | ||||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Dopaminergic synapse | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| 5-Hydroxytryptamine degredation | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Alpha-synuclein signaling | |||
| WikiPathways | Tryptophan metabolism | |||
| Dopamine metabolism | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoa... J Med Chem. 2007 Oct 4;50(20):4909-16. | |||
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