Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08BQI
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| Former ID |
DNC005481
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| Drug Name |
(3,5-Dibromo-4-pentyloxy-phenyl)-acetic acid
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| Synonyms |
SCHEMBL4899221; CHEMBL193152; BDBM18900; ZINC13643198; 3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9c; 2-[3,5-dibromo-4-(pentyloxy)phenyl]acetic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H16Br2O3
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| Canonical SMILES |
CCCCCOC1=C(C=C(C=C1Br)CC(=O)O)Br
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| InChI |
1S/C13H16Br2O3/c1-2-3-4-5-18-13-10(14)6-9(7-11(13)15)8-12(16)17/h6-7H,2-5,8H2,1H3,(H,16,17)
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| InChIKey |
DMILDBSUKKQQDG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thyroid hormone receptor beta (THRB) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Thyroid hormone signaling pathway | ||||
| Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
| Reactome | Nuclear Receptor transcription pathway | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Hematopoietic Stem Cell Differentiation | ||||
| Nuclear Receptors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Thyroid receptor ligands. 3. Design and synthesis of 3,5-dihalo-4-alkoxyphenylalkanoic acids as indirect antagonists of the thyroid hormone receptor. J Med Chem. 2005 May 5;48(9):3114-7. | |||
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