Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08BKH
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| Former ID |
DNC000036
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| Drug Name |
18-Methoxycoronaridine
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| Synonyms |
18-methoxycoronaridine; 308123-60-6; DTXSID40437331
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| Drug Type |
Small molecular drug
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| Indication | Drug abuse [ICD-11: 6C4G.1Z; ICD-10: F19] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H28N2O3
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| Canonical SMILES |
COCCC1CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
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| InChI |
1S/C22H28N2O3/c1-26-10-8-15-11-14-12-22(21(25)27-2)19-17(7-9-24(13-14)20(15)22)16-5-3-4-6-18(16)23-19/h3-6,14-15,20,23H,7-13H2,1-2H3/t14-,15+,20+,22-/m1/s1
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| InChIKey |
DTJQBBHYRQYDEG-SVBQBFEESA-N
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| CAS Number |
CAS 308123-60-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuronal acetylcholine receptor alpha-2/alpha-3 (CHRNA2/A3) | Target Info | Antagonist | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antagonism of alpha 3 beta 4 nicotinic receptors as a strategy to reduce opioid and stimulant self-administration. Eur J Pharmacol. 2002 Mar 1;438(1-2):99-105. | |||
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