Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08BCU
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| Former ID |
DIB005058
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| Drug Name |
U-90042
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| Synonyms |
U 90042; 134516-99-7; U90042; Diimidazo[1,5-a:1',2'-c]quinazoline,11-chloro-5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-; ACMC-20ejs3; SCHEMBL7326473; CTK4B9224; DTXSID40158771; MolPort-023-276-561; ZINC34033310; AKOS024457266; NCGC00378706-01; B7164; J-006546; 11-Chloro-5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2,3-dihydrodiimidazo[1,5-a:1',2'-c]quinazoline
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| Drug Type |
Small molecular drug
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| Indication | Anxiety disorder [ICD-11: 6B00-6B0Z; ICD-10: R45.0] | Terminated | [1] | |
| Company |
Pharmacia & Upjohn Co
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| Structure |
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Download2D MOL |
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| Formula |
C17H13ClN6O
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| Canonical SMILES |
C1CC1C2=NC(=NO2)C3=C4N5CCN=C5C6=C(N4C=N3)C=CC(=C6)Cl
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| InChI |
1S/C17H13ClN6O/c18-10-3-4-12-11(7-10)15-19-5-6-23(15)17-13(20-8-24(12)17)14-21-16(25-22-14)9-1-2-9/h3-4,7-9H,1-2,5-6H2
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| InChIKey |
CLPSAAPUJUVQPP-UHFFFAOYSA-N
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| CAS Number |
CAS 134516-99-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid receptor (GAR) | Target Info | Modulator | [2] |
| References | Top | |||
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| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001470) | |||
| REF 2 | U-90042, a sedative/hypnotic compound that interacts differentially with the GABAA receptor subtypes. J Pharmacol Exp Ther. 1995 Nov;275(2):761-7. | |||
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