Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08AMH
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| Former ID |
DNC002845
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| Drug Name |
1,4-Diethylene Dioxide
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| Synonyms |
1,4-DIOXANE; Dioxane; 123-91-1; p-Dioxane; 1,4-Diethylene dioxide; Diethylene ether; Dioxan; 1,4-Dioxacyclohexane; Dioxanne; Tetrahydro-p-dioxin; Di(ethylene oxide); Tetrahydro-1,4-dioxin; Dioxane-1,4; Diethylene dioxide; Glycol ethylene ether; 1,4-Dioxan; p-Dioxan; Dioxan-1,4; Dioxyethylene ether; Dioksan; Diokan; para-Dioxane; Tetrahydro-para-dioxin; Diossano-1,4; Dioxaan-1,4; p-Dioxin, tetrahydro-; Glycolethylenether; Dioksan [Polish]; Dioxanne [French]; RCRA waste number U108; p-Dioxan [Czech]; 1,4-Dioxanne; NCI-C03689
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C4H8O2
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| Canonical SMILES |
C1COCCO1
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| InChI |
1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2
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| InChIKey |
RYHBNJHYFVUHQT-UHFFFAOYSA-N
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| CAS Number |
CAS 123-91-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
74346, 584710, 584711, 588934, 820333, 821277, 824482, 829375, 829850, 832834, 833176, 833328, 833681, 833817, 833917, 854701, 854783, 3133091, 5111075, 6436358, 7887050, 7887141, 8015865, 8020800, 8028025, 8172066, 10505993, 12078170, 14710353, 14716313, 14716674, 15146328, 17395440, 17403969, 17403970, 17403971, 17403974, 24276784, 24277194, 24849481, 24857850, 24859963, 24861588, 24861676, 24862164, 24866605, 24866610, 24866612, 24867757, 24871907
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| ChEBI ID |
CHEBI:47032
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | B-cell-activating factor (TNFSF13B) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| NF-kappa B signaling pathway | ||||
| Intestinal immune network for IgA production | ||||
| Rheumatoid arthritis | ||||
| Reactome | TNFR2 non-canonical NF-kB pathway | |||
| TNFs bind their physiological receptors | ||||
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | ||||
| WikiPathways | Spinal Cord Injury | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41. | |||
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