Drug Information
Drug General Information | Top | |||
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Drug ID |
D07ZFN
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Former ID |
DNC014573
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Drug Name |
5-Bromo-6-p-tolylamino-1H-pyrimidine-2,4-dione
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Synonyms |
CHEMBL353575; 5-bromo-6-(p-toluidino)uracil; 100763-66-4; 5-Bromo-6-p-tolylamino-1H-pyrimidine-2,4-dione
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C11H10BrN3O2
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Canonical SMILES |
CC1=CC=C(C=C1)NC2=C(C(=O)NC(=O)N2)Br
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InChI |
1S/C11H10BrN3O2/c1-6-2-4-7(5-3-6)13-9-8(12)10(16)15-11(17)14-9/h2-5H,1H3,(H3,13,14,15,16,17)
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InChIKey |
XCZQWOVVHWQUMF-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | DNA topoisomerase (TOP) | Target Info | Inhibitor | [1] |
References | Top | |||
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REF 1 | Inhibitors of Bacillus subtilis DNA polymerase III. Influence of modifications in the pyrimidine ring of anilino- and (benzylamino)pyrimidines. J Med Chem. 1986 May;29(5):676-81. |
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