Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07XWC
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| Former ID |
DIB019235
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| Drug Name |
PMID19831390C14
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| Synonyms |
1116571-01-7; GTPL8151; ZINC45254830; BDBM50299583; AKOS027339246; KB-66522; AS-40572
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C20H21BrN8
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| Canonical SMILES |
CC1CN(CCN1C(=NC2=CC(=CC=C2)Br)NC#N)C3=NC=NC4=C3C(=CN4)C
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| InChI |
1S/C20H21BrN8/c1-13-9-23-18-17(13)19(26-12-25-18)28-6-7-29(14(2)10-28)20(24-11-22)27-16-5-3-4-15(21)8-16/h3-5,8-9,12,14H,6-7,10H2,1-2H3,(H,24,27)(H,23,25,26)/t14-/m0/s1
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| InChIKey |
KSECQYDNQYAZMQ-AWEZNQCLSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | LIM domain kinase-1 (LIMK-1) | Target Info | Inhibitor | [1] |
| LIM domain kinase-2 (LIMK-2) | Target Info | Inhibitor | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J Med Chem. 2009 Nov 12;52(21):6515-8. | |||
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