Drug Information
Drug General Information | Top | |||
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Drug ID |
D07VHS
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Former ID |
DNCL003329
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Drug Name |
Isavuconazole
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Synonyms |
Isavuconazole; 241479-67-4; isavuconazol; BAL 4815; BAL-4815; UNII-60UTO373KE; Isavuconazole [INN]; 60UTO373KE; Isavuconazole(BAL-4815; RO-0094815); RO 0094815; CHEBI:85979; Isavuconazole (INN); RO-0094815; 4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile; 1286730-05-9; 4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile
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Drug Type |
Small molecular drug
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Indication | Candidemia [ICD-11: 1F23.3Y] | Phase 3 | [1] | |
Invasive aspergillosis [ICD-11: 1F20.0; ICD-10: B44.0, B44.8] | Phase 3 | [1] | ||
Invasive candidiasis [ICD-11: 1F23] | Phase 3 | [1] | ||
Company |
Astellas
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Structure |
Download2D MOL |
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Formula |
C22H17F2N5OS
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Canonical SMILES |
CC(C1=NC(=CS1)C2=CC=C(C=C2)C#N)C(CN3C=NC=N3)(C4=C(C=CC(=C4)F)F)O
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InChI |
1S/C22H17F2N5OS/c1-14(21-28-20(10-31-21)16-4-2-15(9-25)3-5-16)22(30,11-29-13-26-12-27-29)18-8-17(23)6-7-19(18)24/h2-8,10,12-14,30H,11H2,1H3/t14-,22+/m0/s1
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InChIKey |
DDFOUSQFMYRUQK-RCDICMHDSA-N
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CAS Number |
CAS 241479-67-4
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PubChem Compound ID | ||||
PubChem Substance ID | ||||
ChEBI ID |
CHEBI:85979
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References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT00634049) Isavuconazole in the Treatment of Renally Impaired Aspergillosis and Rare Fungi. U.S. National Institutes of Health. |
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