Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07VCG
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| Former ID |
DIB003219
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| Drug Name |
Anti-VEGFR 3 mab
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| Synonyms |
Anti-VEGFR 3 mAb (undisclosed indication); Anti-VEGFR 3 mAb (undisclosed indication), PharmAbcine; Vascular endothelial growth factor receptor 3 inhibitor (mAb, undisclosed indication), PharmAbcine
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| Drug Type |
Monoclonal antibody
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Company |
PharmAbcine
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Vascular endothelial growth factor receptor 3 (FLT-4) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Ras signaling pathway | |||
| Rap1 signaling pathway | ||||
| Cytokine-cytokine receptor interaction | ||||
| PI3K-Akt signaling pathway | ||||
| Focal adhesion | ||||
| NetPath Pathway | TNFalpha Signaling Pathway | |||
| Pathway Interaction Database | VEGF and VEGFR signaling network | |||
| VEGFR3 signaling in lymphatic endothelium | ||||
| Reactome | VEGF binds to VEGFR leading to receptor dimerization | |||
| WikiPathways | Signaling by VEGF | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1814). | |||
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