Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07UJA
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| Former ID |
DIB000034
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| Drug Name |
DRL-17822
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| Synonyms |
CETP inhibitor (dyslipidemia/atherosclerosis/cardiovascular diseases), Dr Reddy's
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| Indication | Arteriosclerosis [ICD-11: BD40; ICD-9: 440] | Phase 2 | [1] | |
| Company |
Dr Reddy's Laboratories Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C30H31F6N7
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| Canonical SMILES |
CC1=C2C(=CC=C1)C=C(C(=N2)N(CC3CC3)CC4CC4)CN(CC5=CC(=CC(=C5)C(F)(F)F)C(F)(F)F)C6=NN(N=N6)C
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| InChI |
1S/C30H31F6N7/c1-18-4-3-5-22-12-23(27(37-26(18)22)42(14-19-6-7-19)15-20-8-9-20)17-43(28-38-40-41(2)39-28)16-21-10-24(29(31,32)33)13-25(11-21)30(34,35)36/h3-5,10-13,19-20H,6-9,14-17H2,1-2H3
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| InChIKey |
OCNBSSLDAIWTKS-UHFFFAOYSA-N
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| CAS Number |
CAS 898911-09-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholesteryl ester transfer protein (CETP) | Target Info | Inhibitor | [2] |
| Panther Pathway | CCKR signaling map ST | |||
| Reactome | LDL-mediated lipid transport | |||
| HDL-mediated lipid transport | ||||
| WikiPathways | Statin Pathway | |||
| Lipid digestion, mobilization, and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01388816) A Safety and Efficacy Study of DRL-17822, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Patients With Abnormal Cholesterol Levels. U.S. National Institutes of Health. | |||
| REF 2 | The dyslipidaemia market. Nat Rev Drug Discov. 2014 Nov;13(11):807-8. | |||
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