Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07UFO
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| Former ID |
DIB018530
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| Drug Name |
20-HETE
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| Synonyms |
20-hydroxyeicosatetraenoic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C20H32O3
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| Canonical SMILES |
C(CCC=CCC=CCC=CCC=CCCCC(=O)O)CCO
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| InChI |
1S/C20H32O3/c21-19-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(22)23/h1,3-4,6-7,9-10,12,21H,2,5,8,11,13-19H2,(H,22,23)/b3-1-,6-4-,9-7-,12-10-
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| InChIKey |
NNDIXBJHNLFJJP-DTLRTWKJSA-N
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| CAS Number |
CAS 79551-86-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
4266115, 11038791, 14718392, 14801405, 17395746, 24895546, 39316571, 49964844, 53790793, 57358870, 74666386, 113859256, 126524524, 126525564, 135079354, 137017133, 141469038, 162228697, 164796070, 178100926, 179293501, 184586025, 186022450, 210275257, 210280898, 226819771, 241138961, 250132926, 252371236, 252464960
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| ChEBI ID |
CHEBI:34306
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Short transient receptor potential channel 6 (TRPC6) | Target Info | Activator | [2] |
| Panther Pathway | Alzheimer disease-presenilin pathway | |||
| Pathway Interaction Database | Endothelins | |||
| Nephrin/Neph1 signaling in the kidney podocyte | ||||
| EPO signaling pathway | ||||
| PAR1-mediated thrombin signaling events | ||||
| Reactome | Effects of PIP2 hydrolysis | |||
| TRP channels | ||||
| Role of second messengers in netrin-1 signaling | ||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | |||
| Platelet homeostasis | ||||
| Netrin-1 signaling | ||||
| GPCR downstream signaling | ||||
| Effects of PIP2 hydrolysis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4103). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 491). | |||
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