Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07TXJ
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| Former ID |
DCL000772
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| Drug Name |
Dextofisopam
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| Synonyms |
R-Tofisopam; Dextofisopam (USAN/INN); (5R)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
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| Drug Type |
Small molecular drug
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| Indication | Irritable bowel syndrome [ICD-11: DD91.0; ICD-10: K55-K64, K58; ICD-9: 564.1, 787.91] | Phase 2 | [1] | |
| Company |
Vela Pharmaceuticals
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H26N2O4
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| Canonical SMILES |
CCC1C(=NN=C(C2=CC(=C(C=C12)OC)OC)C3=CC(=C(C=C3)OC)OC)C
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| InChI |
1S/C22H26N2O4/c1-7-15-13(2)23-24-22(14-8-9-18(25-3)19(10-14)26-4)17-12-21(28-6)20(27-5)11-16(15)17/h8-12,15H,7H2,1-6H3/t15-/m0/s1
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| InChIKey |
RUJBDQSFYCKFAA-HNNXBMFYSA-N
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| CAS Number |
CAS 82059-50-5
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| SuperDrug ATC ID |
A10BG03
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| SuperDrug CAS ID |
cas=111025468
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid receptor (GAR) | Target Info | Agonist | [1] |
| Translocator protein (TSPO) | Target Info | Agonist | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| HTLV-I infection | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313. | |||
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