Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07RUH
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| Drug Name |
Beta-phenyl-alpha,beta-unsaturated carbonyl derivative 14
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| Synonyms |
PMID26815044-Compound-78
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| Drug Type |
Small molecular drug
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| Indication | Albinism [ICD-11: EC23.2; ICD-10: E70.3, H90.3] | Patented | [1] | |
| Ephelides [ICD-11: ED61.0] | Patented | [1] | ||
| Melasma [ICD-11: ED60.1] | Patented | [1] | ||
| Menkes disease [ICD-11: 5C64.0; ICD-10: E83.0] | Patented | [1] | ||
| Senile lentigines [ICD-11: ED61.0] | Patented | [1] | ||
| Structure |
 |
Download2D MOL |
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| Formula |
C17H16BrNO3
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| Canonical SMILES |
C1=CC(=CC=C1CCNC(=O)C=CC2=CC(=C(C=C2)O)O)Br
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| InChI |
1S/C17H16BrNO3/c18-14-5-1-12(2-6-14)9-10-19-17(22)8-4-13-3-7-15(20)16(21)11-13/h1-8,11,20-21H,9-10H2,(H,19,22)/b8-4+
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| InChIKey |
QIQBGDXOXRDDBP-XBXARRHUSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Tyrosinase (TYR) | Target's Patent Info | [1] | |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Tyrosinase inhibitors: a patent review (2011-2015).Expert Opin Ther Pat. 2016;26(3):347-62. | |||
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