Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07QWW
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| Former ID |
DCL000758
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| Drug Name |
NBI-34041
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| Drug Type |
Small molecular drug
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| Indication | Eating disorder [ICD-11: 6B82; ICD-9: 307.5] | Phase 1 | [1] | |
| Company |
Neurocrine Biosciences; GlaxoSmithKline
|
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H26Cl2N4
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| Canonical SMILES |
CCCC(CCC)N1CCN2C3=C1C=C(N=C3C(=N2)C4=C(C=C(C=C4)Cl)Cl)C
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| InChI |
1S/C22H26Cl2N4/c1-4-6-16(7-5-2)27-10-11-28-22-19(27)12-14(3)25-21(22)20(26-28)17-9-8-15(23)13-18(17)24/h8-9,12-13,16H,4-7,10-11H2,1-3H3
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| InChIKey |
AKLMUGFDGONMAA-UHFFFAOYSA-N
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| CAS Number |
CAS 268545-87-5
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Corticotropin-releasing factor receptor 2 (CRHR2) | Target Info | Antagonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Panther Pathway | Cortocotropin releasing factor receptor signaling pathway | |||
| Reactome | Class B/2 (Secretin family receptors) | |||
| G alpha (s) signalling events | ||||
| WikiPathways | GPCRs, Class B Secretin-like | |||
| Corticotropin-releasing hormone | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for eating disorder treatment. Expert Opin Emerg Drugs. 2006 May;11(2):315-36. | |||
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