Drug Information
Drug General Information | Top | |||
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Drug ID |
D07QMR
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Former ID |
DNC013293
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Drug Name |
N-(1-(4-phenylbutyl)piperidin-4-yl)-1-naphthamide
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Synonyms |
CHEMBL387952; N-(1-(4-phenylbutyl)piperidin-4-yl)-1-naphthamide
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C26H30N2O
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Canonical SMILES |
C1CN(CCC1NC(=O)C2=CC=CC3=CC=CC=C32)CCCCC4=CC=CC=C4
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InChI |
1S/C26H30N2O/c29-26(25-15-8-13-22-12-4-5-14-24(22)25)27-23-16-19-28(20-17-23)18-7-6-11-21-9-2-1-3-10-21/h1-5,8-10,12-15,23H,6-7,11,16-20H2,(H,27,29)
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InChIKey |
JATDEOORDLHCRO-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
SIDS Susceptibility Pathways | ||||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the ... Bioorg Med Chem Lett. 2007 Mar 15;17(6):1565-9. |
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