Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07PSW
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| Former ID |
DNC004077
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| Drug Name |
N-(4-Phenyl-pyridin-2-yl)-guanidine
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| Synonyms |
CHEMBL54467; N-(4-Phenyl-pyridin-2-yl)-guanidine; Guanidine, N-(4-phenyl-2-pyridinyl)-; 2-(4-Phenyl-2-pyridinyl)guanidine; BDBM50108355
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H12N4
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=NC=C2)N=C(N)N
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| InChI |
1S/C12H12N4/c13-12(14)16-11-8-10(6-7-15-11)9-4-2-1-3-5-9/h1-8H,(H4,13,14,15,16)
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| InChIKey |
LQYVUDQYWIIZAV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tissue-type plasminogen activator (PLAT) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Complement and coagulation cascades | |||
| Transcriptional misregulation in cancer | ||||
| NetPath Pathway | IL5 Signaling Pathway | |||
| Panther Pathway | Blood coagulation | |||
| Plasminogen activating cascade | ||||
| Pathwhiz Pathway | Coagulation | |||
| Pathway Interaction Database | amb2 Integrin signaling | |||
| Beta2 integrin cell surface interactions | ||||
| Reactome | Dissolution of Fibrin Clot | |||
| WikiPathways | Senescence and Autophagy in Cancer | |||
| Complement and Coagulation Cascades | ||||
| Endochondral Ossification | ||||
| Blood Clotting Cascade | ||||
| Dissolution of Fibrin Clot | ||||
| Folate Metabolism | ||||
| Vitamin B12 Metabolism | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Selective urokinase-type plasminogen activator (uPA) inhibitors. Part 1: 2-Pyridinylguanidines. Bioorg Med Chem Lett. 2002 Jan 21;12(2):181-4. | |||
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