Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07PAY
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| Former ID |
DIB013981
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| Drug Name |
B-956
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| Synonyms |
B-1086; B-957
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Terminated | [1] | |
| Company |
Eisai Co Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H36N2O3S2
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| Canonical SMILES |
CC(C)C(C=CC(CC1=CC=CC=C1)C(=O)NC(CCSC)C(=O)O)C=CC(CS)N
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| InChI |
1S/C24H36N2O3S2/c1-17(2)19(11-12-21(25)16-30)9-10-20(15-18-7-5-4-6-8-18)23(27)26-22(24(28)29)13-14-31-3/h4-12,17,19-22,30H,13-16,25H2,1-3H3,(H,26,27)(H,28,29)/b10-9+,12-11+/t19-,20+,21+,22-/m0/s1
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| InChIKey |
IPRQDTJTDYDPBX-KPVQYLNHSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | CAAX farnesyltransferase beta (FNTB) | Target Info | Modulator | [1] |
| KEGG Pathway | Terpenoid backbone biosynthesis | |||
| Biosynthesis of antibiotics | ||||
| NetPath Pathway | TSH Signaling Pathway | |||
| Reactome | Inactivation, recovery and regulation of the phototransduction cascade | |||
| WikiPathways | Visual phototransduction | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibition of human tumor xenograft growth by treatment with the farnesyl transferase inhibitor B956. Cancer Res. 1995 Nov 15;55(22):5310-4. | |||
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