Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07MED
|
|||
| Former ID |
DIB001240
|
|||
| Drug Name |
RG7716
|
|||
| Synonyms |
RG7716; GTPL8529; RG-7716
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Neovascular age-related macular degeneration [ICD-11: 9B78.3Z; ICD-9: 362.5] | Phase 3 | [1] | |
| Choroidal neovascularization [ICD-11: 9B76; ICD-10: H44.2] | Phase 2 | [2], [3] | ||
| Structure |
 |
Download2D MOL |
||
| Formula |
C25H30ClN3O2
|
|||
| Canonical SMILES |
CN(C)CCN1CC(C2=C1C=C(C=C2)Cl)C(=O)N3CCC4(CC3)C5=CC=CC=C5CO4
|
|||
| InChI |
1S/C25H30ClN3O2/c1-27(2)13-14-29-16-21(20-8-7-19(26)15-23(20)29)24(30)28-11-9-25(10-12-28)22-6-4-3-5-18(22)17-31-25/h3-8,15,21H,9-14,16-17H2,1-2H3
|
|||
| InChIKey |
DRMVDBATNZBNEB-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT04777201) A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (AVONELLE-X). U.S. National Institutes of Health. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8529). | |||
| REF 3 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800039789) | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.