Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07KUN
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| Former ID |
DIB015580
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| Drug Name |
Elacestrant
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| Synonyms |
RAD-1901; ER-306323; ER-308698; SERMs, Eisai/Radius; Selective estrogen receptor modulators, Eisai/Radius
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| Indication | Breast cancer [ICD-11: 2C60-2C65; ICD-10: C50, C79.51] | Approved | [1] | |
| Company |
Menarini
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| Structure |
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Download2D MOL |
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| Formula |
C30H38N2O2
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| Canonical SMILES |
CCNCCC1=CC=C(C=C1)CN(CC)C2=C(C=CC(=C2)OC)C3CCC4=C(C3)C=CC(=C4)O
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| InChI |
1S/C30H38N2O2/c1-4-31-17-16-22-6-8-23(9-7-22)21-32(5-2)30-20-28(34-3)14-15-29(30)26-11-10-25-19-27(33)13-12-24(25)18-26/h6-9,12-15,19-20,26,31,33H,4-5,10-11,16-18,21H2,1-3H3/t26-/m1/s1
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| InChIKey |
SIFNOOUKXBRGGB-AREMUKBSSA-N
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| CAS Number |
CAS 722533-56-4
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 217639. | |||
| REF 2 | RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models. Anticancer Drugs. 2015 Oct;26(9):948-56. | |||
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