Drug Information
Drug General Information | Top | |||
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Drug ID |
D07HOH
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Former ID |
DNCL002684
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Drug Name |
MM-398
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Indication | Pancreatic cancer [ICD-11: 2C10; ICD-9: 185] | Phase 3 | [1] | |
Company |
Merrimack Pharmaceuticals
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Structure |
Download2D MOL
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Formula |
C45H60N4O41S8
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Canonical SMILES |
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.C(C1C(C(C(C(O1)OC2(C(C(C(O2)COS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O)COS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O
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InChI |
1S/C33H38N4O6.C12H22O35S8/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;13-48(14,15)37-1-4-6(43-51(22,23)24)8(45-53(28,29)30)9(46-54(31,32)33)11(40-4)42-12(3-39-50(19,20)21)10(47-55(34,35)36)7(44-52(25,26)27)5(41-12)2-38-49(16,17)18/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;4-11H,1-3H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36)/t33-;4-,5-,6-,7+,8+,9-,10+,11-,12+/m01/s1
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InChIKey |
PMZSPINGJVBHAT-DJBCQDJXSA-N
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CAS Number |
CAS 1361317-83-0
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PubChem Compound ID |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01494506) Study of MM-398 With or Without 5-Fluorouracil and Leucovorin, Versus 5-Fluorouracil and Leucovorin in Patients With Metastatic Pancreatic Cancer. U.S. National Institutes of Health. |
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