Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07FRX
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| Former ID |
DNC014631
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| Drug Name |
6-Thiophen-3-yl-imidazo[2,1-b]thiazole
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| Synonyms |
6-Thiophen-3-yl-imidazo[2,1-b]thiazole; 163851-59-0; CHEMBL273842; AKOS005145119
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H6N2S2
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| Canonical SMILES |
C1=CSC=C1C2=CN3C=CSC3=N2
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| InChI |
1S/C9H6N2S2/c1-3-12-6-7(1)8-5-11-2-4-13-9(11)10-8/h1-6H
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| InChIKey |
QNYBFCDYFVERKH-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | NADH dehydrogenase (MT-ND3) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Oxidative phosphorylation | |||
| Metabolic pathways | ||||
| Parkinson's disease | ||||
| WikiPathways | Oxidative phosphorylation | |||
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ||||
| Electron Transport Chain | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Thienylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase. J Med Chem. 1995 Mar 31;38(7):1090-7. | |||
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