Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07EHB
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| Former ID |
DIB001729
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| Drug Name |
Latrunculin B
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| Synonyms |
INS-115644; Cytoskeleton-targeting compounds (glaucoma), Wisconsin Alumni Research Foundation (WARF)/Inspire
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| Drug Type |
Small molecular drug
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| Indication | Glaucoma/ocular hypertension [ICD-11: 9C61; ICD-9: 365] | Phase 1 | [1] | |
| Company |
University of Wisconsin-Madison
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| Structure |
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Download2D MOL |
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| Formula |
C20H29NO5S
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| Canonical SMILES |
CC1CCC2CC(CC(O2)(C3CSC(=O)N3)O)OC(=O)C=C(CCC=C1)C
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| InChI |
1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9-/t13-,15-,16-,17+,20-/m1/s1
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| InChIKey |
NSHPHXHGRHSMIK-JRIKCGFMSA-N
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| CAS Number |
CAS 76343-94-7
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:49703
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00443924) Study of INS115644 Ophthalmic Solution in Subjects With Ocular Hypertension or Glaucoma. U.S. National Institutes of Health. | |||
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