Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07DSN
|
|||
| Former ID |
DIB014767
|
|||
| Drug Name |
BIIB 033
|
|||
| Drug Type |
Antibody
|
|||
| Indication | Multiple sclerosis [ICD-11: 8A40; ICD-9: 340] | Phase 2 | [1] | |
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Leucine-rich repeat neuronal protein 1 (LINGO1) | Target Info | . | [1] |
| Reactome | Axonal growth inhibition (RHOA activation) | |||
| WikiPathways | BDNF signaling pathway | |||
| Signalling by NGF | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Randomized phase I trials of the safety/tolerability of anti-LINGO-1 monoclonal antibody BIIB033. Neurol Neuroimmunol Neuroinflamm. 2014 Aug 21;1(2):e18. | |||
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