Drug Information
Drug General Information | Top | |||
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Drug ID |
D07DAX
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Former ID |
DNC009236
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Drug Name |
2,7-Dinitroantraquinone
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Synonyms |
2,7-Dinitroanthraquinone; 605-28-7; 2,7-Dinitroantraquinone; EINECS 210-084-2; 2,7-dinitro-9,10-anthraquinone; 2,7- Dinitroanthrachinon; AC1L2B0Y; SCHEMBL2772220; CHEMBL493255; AC1Q21I1; CTK5B1648; DTXSID00209233; XFLONXIGNOXKCG-UHFFFAOYSA-N; ZINC5845160; 2,7-dinitroanthracene-9,10-dione
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C14H6N2O6
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Canonical SMILES |
C1=CC2=C(C=C1[N+](=O)[O-])C(=O)C3=C(C2=O)C=CC(=C3)[N+](=O)[O-]
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InChI |
1S/C14H6N2O6/c17-13-9-3-1-7(15(19)20)5-11(9)14(18)12-6-8(16(21)22)2-4-10(12)13/h1-6H
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InChIKey |
XFLONXIGNOXKCG-UHFFFAOYSA-N
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CAS Number |
CAS 605-28-7
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
KEGG Pathway | HTLV-I infection | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
Regulation of Telomerase | ||||
IL2 signaling events mediated by PI3K | ||||
Regulation of nuclear beta catenin signaling and target gene transcription | ||||
HIF-1-alpha transcription factor network | ||||
Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
WikiPathways | TGF beta Signaling Pathway | |||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Telomere Maintenance |
References | Top | |||
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REF 1 | Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives. Bioorg Med Chem. 2008 Jul 15;16(14):6976-86. |
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