Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07AOY
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| Former ID |
DNCL003528
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| Drug Name |
Avarofloxacin
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| Synonyms |
JNJ-Q2
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| Drug Type |
Small molecular drug
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| Indication | Bacterial pneumonia [ICD-11: CA40.0] | Discontinued in Phase 2 | [1] | |
| Company |
Furiex pharmaceuticals
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| Structure |
 |
Download2D MOL |
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| Formula |
C21H23F2N3O4
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| Canonical SMILES |
COC1=C2C(=CC(=C1N3CCCC(=C(CN)F)C3)F)C(=O)C(=CN2C4CC4)C(=O)O
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| InChI |
1S/C21H23F2N3O4/c1-30-20-17-13(19(27)14(21(28)29)10-26(17)12-4-5-12)7-15(22)18(20)25-6-2-3-11(9-25)16(23)8-24/h7,10,12H,2-6,8-9,24H2,1H3,(H,28,29)/b16-11+
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| InChIKey |
VMKVDAAFMQKZJS-LFIBNONCSA-N
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| CAS Number |
CAS 878592-87-1
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Staphylococcus Topoisomerase IV (Stap-coc parC) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032241) | |||
| REF 2 | Antistaphylococcal activities of the new fluoroquinolone JNJ-Q2. Antimicrob Agents Chemother. 2011 Dec;55(12):5512-21. | |||
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