Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06ZPS
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| Drug Name |
Oxyphenbutazone
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| Synonyms |
Tandearil
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| Drug Type |
Small molecular drug
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| Indication | Arthritis [ICD-11: FA20] | Approved | [1] | |
| Company |
Novartis Pharmaceuticals Corp
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H20N2O3
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| Canonical SMILES |
CCCCC1C(=O)N(N(C1=O)C2=CC=C(C=C2)O)C3=CC=CC=C3
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| InChI |
1S/C19H20N2O3/c1-2-3-9-17-18(23)20(14-7-5-4-6-8-14)21(19(17)24)15-10-12-16(22)13-11-15/h4-8,10-13,17,22H,2-3,9H2,1H3
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| InChIKey |
HFHZKZSRXITVMK-UHFFFAOYSA-N
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| CAS Number |
CAS 129-20-4
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:76258
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Serum albumin (ALB) | Target Info | Modulator | [2] |
| Pathway Interaction Database | FOXA2 and FOXA3 transcription factor networks | |||
| Reactome | Platelet degranulation | |||
| Recycling of bile acids and salts | ||||
| HDL-mediated lipid transport | ||||
| Scavenging of heme from plasma | ||||
| WikiPathways | Human Complement System | |||
| Binding and Uptake of Ligands by Scavenger Receptors | ||||
| Lipid digestion, mobilization, and transport | ||||
| Transport of vitamins, nucleosides, and related molecules | ||||
| Bile acid and bile salt metabolism | ||||
| Folate Metabolism | ||||
| Vitamin B12 Metabolism | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Effect of albumin conformation on binding of phenylbutazone and oxyphenbutazone to human serum albumin. J Pharm Sci. 1982 Feb;71(2):241-4. | |||
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