Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06ZEO
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| Former ID |
DNCL003391
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| Drug Name |
Vericiguat
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| Synonyms |
Vericiguat; 1350653-20-1; UNII-LV66ADM269; BAY-1021189; Methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate; BAY1021189; LV66ADM269; MK-1242; Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate; methyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate; Methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)pyrimidin-5-yl)carbam
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| Drug Type |
Small molecular drug
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| Indication | Heart failure [ICD-11: BD10-BD13] | Approved | [1] | |
| Company |
Bayer HealthCare Pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C19H16F2N8O2
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| Canonical SMILES |
COC(=O)NC1=C(N=C(N=C1N)C2=NN(C3=C2C=C(C=N3)F)CC4=CC=CC=C4F)N
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| InChI |
1S/C19H16F2N8O2/c1-31-19(30)25-14-15(22)26-17(27-16(14)23)13-11-6-10(20)7-24-18(11)29(28-13)8-9-4-2-3-5-12(9)21/h2-7H,8H2,1H3,(H,25,30)(H4,22,23,26,27)
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| InChIKey |
QZFHIXARHDBPBY-UHFFFAOYSA-N
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| CAS Number |
CAS 1350653-20-1
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:142432
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Soluble guanylyl cyclase (GUCY2D) | Target Info | Modulator | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2021 | |||
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