Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06YXT
|
|||
| Former ID |
DNC001030
|
|||
| Drug Name |
NNC 711
|
|||
| Synonyms |
NO-711 hydrochloride; 145645-62-1; UNII-500M0G931K; 1-(2-(((Diphenylmethylene)amino)oxy)ethyl)-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid; 500M0G931K; 1-[2-[[(Diphenylmethylene)imino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride hydrochloride; 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE; C21H23ClN2O3; 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-(2-(((diphenylmethylene)amino)oxy)ethyl)-,
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H23ClN2O3
|
|||
| Canonical SMILES |
C1CN(CC(=C1)C(=O)O)CCON=C(C2=CC=CC=C2)C3=CC=CC=C3.Cl
|
|||
| InChI |
1S/C21H22N2O3.ClH/c24-21(25)19-12-7-13-23(16-19)14-15-26-22-20(17-8-3-1-4-9-17)18-10-5-2-6-11-18;/h1-6,8-12H,7,13-16H2,(H,24,25);1H
|
|||
| InChIKey |
YZYRTEYMUTWJPL-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 145645-62-1
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
5629885, 7980150, 8152782, 11111506, 11114214, 14827723, 26752247, 29223608, 47217005, 47515547, 48185197, 50070827, 50104957, 76370773, 85788754, 90340568, 103590864, 103980515, 104306628, 124750070, 124880802, 124880803, 124880804, 126407933, 128699097, 134339511, 142472667, 162474796, 164154950, 172649439, 178101384, 179235722, 198951897, 231739519
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid uptake (GABAU) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4669). | |||
| REF 2 | Effects of NNC 711, a GABA uptake inhibitor, on pentylenetetrazol-induced seizures in developing and adult rats. Naunyn Schmiedebergs Arch Pharmacol. 1998 Sep;358(3):334-41. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.