Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06YSI
|
|||
| Former ID |
DNC002248
|
|||
| Drug Name |
ISIS 222001
|
|||
| Drug Type |
Antisense drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Company |
Isis Pharmaceuticals
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | HIF2-alpha messenger RNA (EPAS1 mRNA) | Target Info | . | [1] |
| KEGG Pathway | Pathways in cancer | |||
| Renal cell carcinoma | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
| Reactome | Regulation of gene expression by Hypoxia-inducible Factor | |||
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | ||||
| Transcriptional regulation of pluripotent stem cells | ||||
| WikiPathways | Transcriptional regulation of pluripotent stem cells | |||
| Regulation of Hypoxia-inducible Factor (HIF) by Oxygen | ||||
| Adipogenesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | US patent application no. 7,217,572, Modulation of HIF1.alpha. and HIF2.alpha. expression. | |||
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