Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06XRS
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| Former ID |
DNC007756
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| Drug Name |
N-(2-(4-chlorobenzyloxy)-5-bromobenzyl)ethanamine
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| Synonyms |
CHEMBL233385; N-[[5-bromo-2-[(4-chlorophenyl)methoxy]phenyl]methyl]ethanamine; AC1NFZZ9; N-(2-(4-chlorobenzyloxy)-5-bromobenzyl)ethanamine; SCHEMBL5700011; ZINC8227211; BDBM50205773; AKOS002615028; MCULE-5007100183; Benzenemethanamine, 5-bromo-2-[(4-chlorophenyl)methoxy]-N-ethyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H17BrClNO
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| Canonical SMILES |
CCNCC1=C(C=CC(=C1)Br)OCC2=CC=C(C=C2)Cl
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| InChI |
1S/C16H17BrClNO/c1-2-19-10-13-9-14(17)5-8-16(13)20-11-12-3-6-15(18)7-4-12/h3-9,19H,2,10-11H2,1H3
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| InChIKey |
ORVDFXFQIBURPI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | C-C chemokine receptor type 5 (CCR5) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Chemokine signaling pathway | ||||
| Endocytosis | ||||
| Toxoplasmosis | ||||
| Viral carcinogenesis | ||||
| NetPath Pathway | TSLP Signaling Pathway | |||
| TCR Signaling Pathway | ||||
| IL2 Signaling Pathway | ||||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Pathway Interaction Database | IL12-mediated signaling events | |||
| Reactome | Binding and entry of HIV virion | |||
| Chemokine receptors bind chemokines | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | TCR Signaling Pathway | |||
| GPCRs, Class A Rhodopsin-like | ||||
| HIV Life Cycle | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | CCR5 receptor antagonists: discovery and SAR of novel 4-hydroxypiperidine derivatives. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1883-7. | |||
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